Azidothiorphan

Overview

Azidothiorphan is an irreversible photoaffinity ligand and Endopeptidase 24.11 inhibitor, with a K i value of 0.75 nM against Endopeptidase 24.11. Upon UV irradiation, Azidothiorphan binds to the active site of enkephalinase, resulting in irreversible loss of enzyme activity. Azidothiorphan produces long-lasting analgesic effects in mice. Azidothiorphan can be used in pain-related research.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Pain | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Neprilysin

Product Information

• Catalog No.: HY-165466
• CAS No.: 83960-29-6
• Molecular Formula: C12H14N4O3S
• Molecular Weight: 294.33
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source