AWD 122-60 is a potassium channel blocker and calcium sensitizer, with IC 50 values of 11 μM and 29 μM, respectively, against mouse skeletal muscle ATP-sensitive potassium ( K ATP ) channels. AWD 122-60 exerts potent positive inotropic activity. AWD 122-60 exhibits antiarrhythmic activity in vivo and prolongs myocardial refractory period in vitro. AWD 122-60 can be used for research related to arrhythmias.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Heart Disease | Products > Disease Areas > Arrhythmias | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Potassium Channel | Products > Signaling Pathways > Calcium Channel
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