E2072

Overview

E2072 is a selective, orally active competitive inhibitor of glutamate carboxypeptidase II ( GCPII ) with a K i of 10 nM. E2072 alleviates established thermal hyperalgesia in a rat model of chronic constriction injury. E2072 prevents oxaliplatin-induced reductions in nerve conduction velocity and amplitude in mice. E2072 is applicable to research related to neuropathic pain and neuropathy.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Pain | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Carboxypeptidase

Product Information

• Catalog No.: HY-165571
• CAS No.: 378242-00-3
• Molecular Formula: C16H14O4S
• Molecular Weight: 302.34
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source