(Rac)-Mefloquine

(Rac)-Mefloquine
  • CAS No.:49752-90-1
  • Formula:C17H16F6N2O
  • M.W.:378.32

Overview

(Rac)-Mefloquine ((Rac)-Mefloquin) is an orally active NF-κB inhibitor. (Rac)-Mefloquine inhibits the NF-κB and IKK signaling pathways, suppresses NF-κB -Luc luciferase activity, blocks the activation of p65 and IκBα , and reduces the expression of downstream target genes of NF-κB . (Rac)-Mefloquine activates apoptosis -related factors and induces apoptosis in tumor cells. (Rac)-Mefloquine functions as a tumor cell inhibitor. (Rac)-Mefloquine can be used for the research of colorectal cancer .

Application

Products | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Colorectal Cancer | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > IKK | Products > Signaling Pathways > Apoptosis

Product Information

  • Catalog No.: HY-17437C
  • CAS No.: 49752-90-1
  • Molecular Formula: C17H16F6N2O
  • Molecular Weight: 378.32
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source


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