BD-1063

Overview

BD-1063 is a selective σ-1 receptor antagonist with inhibitory activity against TRPC5 and TRPM3 . BD-1063 exerts anti-hyperalgesic and anti-allodynic effects by inhibiting sustained calcium influx mediated by TRPC5 and TRPM3, and reverses the effects of Carrageenan ( HY-125474 ). BD-1063 also significantly reduces excessive ethanol self-administration behavior. BD-1063 is widely used in studies on the mechanisms underlying neuropathic pain, inflammatory hyperalgesia, and alcohol abuse and dependence.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Pain | Products > Disease Areas > Behavioral Addiction | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Sigma Receptor | Products > Signaling Pathways > TRP Channel

Product Information

• Catalog No.: HY-18101
• CAS No.: 150208-28-9
• Molecular Formula: C13H18Cl2N2
• Molecular Weight: 273.20
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source