ATM-IN-13

Overview

ATM-IN-13 (A36) is an orally active, selective ATM kinase inhibitor with a human IC 50 of 0.3 nM. ATM-IN-13 blocks the ATM -mediated DNA double-strand break repair signaling pathway, reduces the phosphorylation levels of ATM and p53 , and inhibits ATM -dependent DNA damage response. ATM-IN-13 can be used in the research of colorectal cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > ATM/ATR

Product Information

• Catalog No.: HY-181786
• CAS No.: 3104731-13-4
• Molecular Formula: C27H33N5O
• Molecular Weight: 443.58
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source