AChE/MAO-B-IN-9

Overview

AChE/MAO-B-IN-9 (Compound E12) is an orally active, selective, reversible, non-competitive AChE and MAO-B inhibitor, with an IC 50 of 0.156 μM against electric eel AChE . AChE/MAO-B-IN-9 inhibits Aβ40/42 fibril formation, promotes Aβ fibril depolymerization, and inhibits Tau protein fibril formation. AChE/MAO-B-IN-9 exerts antioxidant and neuroprotective effects, and improves scopolamine (HY-N0296)-induced memory impairment in mice. AChE/MAO-B-IN-9 can be used for the research of Alzheimer's disease.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Alzheimer's Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Cholinesterase (ChE) | Products > Signaling Pathways > Monoamine Oxidase | Products > Signaling Pathways > Amyloid-β | Products > Signaling Pathways > Tau Protein

Product Information

• Catalog No.: HY-181861
• CAS No.: 2341935-88-2
• Molecular Formula: C21H20FN3O3
• Molecular Weight: 381.40
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source