D-DT/MIF-1-IN-1

Overview

D-DT/MIF-1-IN-1 (Compound 4h) is a non-competitive, non-covalent inhibitor of MIF-1 and D-DT , with IC 50 values of 2.4 μM and 4.0 μM against D-DT , and an IC 50 value of 9.8 μM against MIF-1 . D-DT/MIF-1-IN-1 inhibits D-DT -induced phosphorylation of ERK and exerts antiproliferative activity in non-small cell lung cancer cells.

Application

Products | Products > Disease Areas > Respiratory Cancer | Products > Disease Areas > Non-Small Cell Lung Cancer | Products > Disease Areas > Cancer | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Lung Cancer | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Macrophage migration inhibitory factor (MIF) | Products > Signaling Pathways > ERK

Product Information

• Catalog No.: HY-181912
• CAS No.: 1461756-61-5
• Molecular Formula: C12H10ClNO3
• Molecular Weight: 251.67
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source