GIT1-IN-1

Overview

GIT1-IN-1 is an inhibitor of ARF GTPase-activating protein 1 ( GIT1 ) with a K D of 6.2 μM. GIT1-IN-1 induces apoptosis ( apoptosis ) in liver and colon cancer cells, arrests the cell cycle at the G2/M phase, and inhibits cell proliferation, colony formation and migration. GIT1-IN-1 inhibits the activities of MEK and ERK , reduces the expression level of cyclin D1 , and stabilizes cyclin B1 protein in liver and colon cancer cells. GIT1-IN-1 can be used in the research of liver cancer and colon cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Disease Areas > Liver Cancer | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > MAPK/ERK Pathway | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > ERK | Products > Signaling Pathways > CDK | Products > Signaling Pathways > Ras | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > MEK

Product Information

• Catalog No.: HY-181978
• CAS No.: 844464-54-6
• Molecular Formula: C21H20N4O4S
• Molecular Weight: 424.47
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source