NAMPT activator-9

Overview

NAMPT activator-9 (Compound DIPM) is an allosteric, non-competitive NAMPT activator, with an EC 50 of 3.366 μM against hNAMPT. NAMPT activator-9 enhances the enzymatic activity of NAMPT via an allosteric, non-competitive mechanism. NAMPT activator-9 increases intracellular NAD + levels. NAMPT activator-9 restores myotube diameter and reduces the expression of atrophy markers Atrogin-1 and MuRF1 . NAMPT activator-9 is applicable to research related to muscle atrophy.

Application

Products | Products > Disease Areas > Musculoskeletal and Skin Disease | Products > Disease Areas > Muscle Disease | Products > Disease Areas > Muscular Dystrophy | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > NAMPT | Products > Signaling Pathways > E1/E2/E3 Enzyme

Product Information

• Catalog No.: HY-182062
• CAS No.: 931366-46-0
• Molecular Formula: C17H15N5O
• Molecular Weight: 305.33
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source