MG16 is a prodrug of 10-Methoxycamptothecin ( HY-N0446 ). MG16 downregulates CDK6 and upregulates ASK1 . MG16 induces cell cycle arrest and Apoptosis . MG16 exhibits anticancer activity against Lewis lung carcinoma, small cell lung cancer , and non-small cell lung cancer .
Products | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Lung Cancer | Products > Disease Areas > Respiratory Cancer | Products > Disease Areas > Small Cell Lung Cancer | Products > Disease Areas > Non-Small Cell Lung Cancer | Products > Disease Areas > Cancer | Products > Signaling Pathways > Others | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Drug Derivative | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > CDK | Products > Signaling Pathways > ASK1
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