BTK-IN-48 is a BTK inhibitor with an IC 50 of 1.14 μM. BTK-IN-48 inhibits recombinant BTK and c-Src , and exerts moderate inhibitory effects on LCK , BMX/ETK , FLT3 and PIM1 . BTK-IN-48 can be used in the research of B-cell malignancies and autoimmune diseases.
Products | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Disease Areas > Autoimmune Disease | Products > Disease Areas > Diffuse Large B-cell Lymphoma | Products > Disease Areas > Cancer | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > JAK/STAT Signaling | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Btk | Products > Signaling Pathways > Src | Products > Signaling Pathways > BMX Kinase | Products > Signaling Pathways > FLT3 | Products > Signaling Pathways > Pim
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