CTX-439

Overview

CTX-439 is an orally active, ATP-competitive small-molecule inhibitor of CDK12 and CDK13 , with an IC 50 of 3.1 nM and a K d of 0.38 nM against CDK12 , and an IC 50 of 9.2 nM against CDK13 . CTX-439 induces DNA damage and apoptosis in tumor cells. CTX-439 is applicable for the research of breast cancer and ovarian cancer .

Application

Products | Products > Disease Areas > Urogenital Cancer | Products > Disease Areas > Cancer | Products > Disease Areas > Urogenital Disease | Products > Disease Areas > Breast Cancer | Products > Disease Areas > Ovarian Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > CDK | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-182312
• CAS No.: 2377487-13-1
• Molecular Formula: C30H32F3N9O4S
• Molecular Weight: 671.69
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source