BTA-EG6

Overview

BTA-EG6 is a brain-penetrant aggregated amyloid-β ( Aβ ) peptide binder with a K d of 290 nM for Aβ1-42. BTA-EG6 binds to aggregated Aβ and forms protein-resistive coatings that block interactions between Aβ and catalase. BTA-EG6 protects neuroblastoma cells from Aβ-induced toxicity and oxidative stress, and inhibits Aβ-induced increases in cellular hydrogen peroxide (H 2 O 2 ) levels. BTA-EG6 can be used for the research of alzheimer’s disease (AD).

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Alzheimer's Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Amyloid-β

Product Information

• Catalog No.: HY-182328
• CAS No.: 921193-29-5
• Molecular Formula: C26H36N2O6S
• Molecular Weight: 504.64
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source