PF-07245303

Overview

PF-07245303 is a ITK / TRK inhibitor. PF-07245303 reduces the production of inflammatory cytokines such as IL-4 and IFNγ , and inhibits the phosphorylation of PLCγ1 . PF-07245303 inhibits nerve growth factor-induced basophil activation and the phosphorylation of TRKA . PF-07245303 reduces oxazolone-induced ear swelling in mouse ear tissues. PF-07245303 is applicable to research related to atopic dermatitis.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Signaling Pathways > Protein Tyrosine Kinase/RTK | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Itk | Products > Signaling Pathways > Trk Receptor | Products > Signaling Pathways > Interleukin Related | Products > Signaling Pathways > IFNAR

Product Information

• Catalog No.: HY-182335
• CAS No.: 2655556-75-3
• Molecular Formula: C25H32N6O2
• Molecular Weight: 448.56
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.
• Availability: In-stock

Source

Original product source