SGK1-IN-8

Overview

SGK1-IN-8 (compound 55) is a SGK1 and GSK3β inhibitor, with an IC 50 of 0.11 μM against human SGK1 and an IC 50 of 3.39 μM against human GSK3β . SGK1-IN-8 inhibits the catalytic activities of SGK1 and GSK3β , and reduces the phosphorylation level of TAU protein at the Ser214 site. SGK1-IN-8 is available for the research of Alzheimer's disease.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Alzheimer's Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > SGK

Product Information

• Catalog No.: HY-182342
• CAS No.: 3109982-48-8
• Molecular Formula: C18H13ClN4O
• Molecular Weight: 336.78
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source