CHDI-340246

Overview

CHDI-340246 is an orally active kynurenine monooxygenase ( KMO ) inhibitor. CHDI-340246 blocks KMO activity, alters the metabolic flux of the kynurenine pathway, inhibits the production of 3-hydroxykynurenine and quinolinic acid, elevates the levels of kynurenine and kynurenic acid, and restores electrophysiological abnormalities in transgenic mouse models of Huntington's disease. CHDI-340246 can be used in studies related to Huntington's disease.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Huntington's Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > KMO

Product Information

• Catalog No.: HY-182456
• CAS No.: 1426319-74-5
• Molecular Formula: C14H11ClN2O3
• Molecular Weight: 290.70
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source