Gambogin is an α-glucosidase inhibitor, found in the resin and dry latex of Garcinia hanburyi . Gambogin exists as an inseparable diastereomeric pair of C-2 epimers (8a and 8b), with 8a having an α-glucosidase inhibitory IC 50 of 209.2 μM and 8b showing α-glucosidase inhibitory IC 50 > 300 μM. Gambogin can be used for the research of type 2 diabetes and cervical cancer .
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