AL-6556 is a full agonist of the DP receptor and a partial agonist of the EP2 receptor . AL-6556 has an EC 50 of 799 nM for bovine DP , a K i of 3200 nM for human DP , and an EC 50 of 1180 nM for human EP2 , with selectivity over EP3, FP , IP , TP and 19 non-prostaglandin receptors. AL-6556 stimulates cAMP production via receptor activation and reduces intraocular pressure through aqueous humor inflow and outflow mechanisms. AL-6556 can be used in research related to ocular hypertension and glaucoma.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Visual System Disease | Products > Disease Areas > Glaucoma | Products > Disease Areas > Ocular Hypertension | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Prostaglandin Receptor
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