Tyr-Ala-N-(1,3-dimethylbutyl)glycinamide

Overview

Tyr-Ala-N-(1,3-dimethylbutyl)glycinamide is a μ/δ opioid receptor ligand with high μ opioid receptor selectivity and agonist activity. Tyr-Ala-N-(1,3-dimethylbutyl)glycinamide has an IC 50 of 237 nM for μ receptors and 1050 nM for δ receptors. Tyr-Ala-N-(1,3-dimethylbutyl)glycinamide shows K i values of 17 nM for μ receptors and 480 nM for δ receptors. Tyr-Ala-N-(1,3-dimethylbutyl)glycinamide inhibits electrically evoked contractions of guinea pig ileum and mouse vas deferens. Tyr-Ala-N-(1,3-dimethylbutyl)glycinamide serves as a starting compound for structure-activity relationship investigations of μ receptor recognition.

Application

Products | Products > Disease Areas > Urogenital Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Endocrinology | Products > Signaling Pathways > Opioid Receptor

Product Information

• Catalog No.: HY-182563
• CAS No.: 72732-17-3
• Molecular Formula: C20H32N4O4
• Molecular Weight: 392.49
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source