HBK001

Overview

HBK001 is an orally active and selective dual GPR119 agonist and DPP-IV inhibitor. HBK001 triggers cAMP production, PKA activation, CREB phosphorylation, glucose-stimulated insulin secretion, plasma incretin elevation, β-cell proliferation, and β-cell function gene up-regulation. HBK001 reduces blood glucose, ameliorates hyperglycemia, improves glucose tolerance, and enhances islet morphology. HBK001 can be used for the research of type 2 diabetes mellitus.

Application

Products | Products > Disease Areas > Glucose Metabolism | Products > Disease Areas > Type 1 Diabetes | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Metabolic or Endocrine Disease | Products > Disease Areas > Autoimmune Disease | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Metabolic Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > GPR119 | Products > Signaling Pathways > Dipeptidyl Peptidase

Product Information

• Catalog No.: HY-182580
• CAS No.: 1942922-78-2
• Molecular Formula: C30H38N10O3
• Molecular Weight: 586.69
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source