Tracizoline is an orally active I2-imidazoline receptor agonist. Tracizoline functionally modulates I2-imidazoline receptors, regulates hippocampal FADD cell fate adaptor, attenuates mechanical and thermal hyperalgesia, activates α 2 A-adrenergic receptors with very weak partial agonism, and induces antidepressant-like activity via 5-HT 1 A receptor activation. Tracizoline can be used for the research of inflammatory pain, neuropathic pain, and depression.
Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Depression | Products > Disease Areas > Pain | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Imidazoline Receptor | Products > Signaling Pathways > 5-HT Receptor | Products > Signaling Pathways > Adrenergic Receptor
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