KLK6-IN-1

Overview

KLK6-IN-1 is a reversible small‑molecule inhibitor of KLK6 , KLK1 , and plasmin . KLK6-IN-1 shows IC 50 values of 1.57 μM (KLK6), 5.1 μM ( KLK1 ), 7.4 μM (plasmin), and K i values of 0.8 μM (KLK6), 2.4 μM ( KLK1 ), 1.3 μM (plasmin). KLK6-IN-1 is highly selective for KLK6 and its proteolytic network. KLK6-IN-1 induces oligodendrocyte differentiation by promoting oligodendrocyte precursor cell maturation. KLK6-IN-1 can be used for the research of multiple sclerosis.

Application

Products | Products > Disease Areas > Multiple Sclerosis | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Autoimmune Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Kallikrein | Products > Signaling Pathways > Plasminogen/Plasmin

Product Information

• Catalog No.: HY-182600
• CAS No.: 2370980-52-0
• Molecular Formula: C18H17ClN2O2
• Molecular Weight: 328.79
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source