MC-100093

Overview

MC-100093 is an orally active, blood-brain barrier-permeable GLT-1 expression upregulator . MC-100093 upregulates the expression of GLT-1 and xCT in rats, and alleviates fentanyl-induced GLT-1 downregulation, IL-6 upregulation and motor hyperactivity. MC-100093 upregulates GLT-1 expression and enhances glutamate uptake in astrocyte-neuron co-culture systems. MC-100093 reduces ethanol consumption and preference, and exerts gender-specific antidepressant-like effects . MC-100093 can be used in studies related to fentanyl overdose, mood disorders and alcohol use disorders.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Depression | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > EAAT | Products > Signaling Pathways > Interleukin Related

Product Information

• Catalog No.: HY-182601
• CAS No.: 1639784-02-3
• Molecular Formula: C13H23N3O3
• Molecular Weight: 269.34
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source