NCGC00063279

Overview

NCGC00063279 is a reversible Werner Syndrome Helicase-Nuclease ( WRN ) helicase inhibitor with modest selectivity over BLM and FANCJ helicases, and does not inhibit WRN exonuclease activity at active concentrations. NCGC00063279 inhibits Hematopoietic Protein Tyrosine Phosphatase ( HePTP ) and reduces proliferation of cancer cells. NCGC00063279 can be used for the research of osteosarcoma.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > DNA/RNA Synthesis | Products > Signaling Pathways > Phosphatase

Product Information

• Catalog No.: HY-182634
• CAS No.: 714932-54-4
• Molecular Formula: C18H13N3O3
• Molecular Weight: 319.31
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source