MRS7469

Overview

MRS7469 is a highly selective A1 adenosine receptor ( A1AR ) agonist with over 2000-fold selectivity over other adenosine receptor subtypes. MRS7469 stably binds to the orthosteric binding site of A1AR , and exhibits extremely high affinity for both humans and mice (e.g., human pK i is 8.67, mouse pK i is 9.43). By activating central A1AR , MRS7469 significantly induces hypothermia, motor inhibition and psychomotor dysfunction, and can be widely used in research related to depression and other relevant fields.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Depression | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Adenosine Receptor

Product Information

• Catalog No.: HY-182687
• CAS No.: 2257428-48-9
• Molecular Formula: C21H28ClN5O3
• Molecular Weight: 433.93
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source