AZD0011

Overview

AZD0011, a prodrug of AZD0011-PL ( HY-182718 ), is an orally active arginase 1 inhibitor with an IC 50 of 328 nM. AZD0011 undergoes in vivo hydrolysis to release an arginase inhibitor payload, inhibiting arginine hydrolysis, increases arginine levels in plasma and the tumor microenvironment. AZD0011 restores innate immune function and inhibits tumor growth. AZD0011 can be used for the research of cancer , such as fibrosarcoma.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Arginase

Product Information

• Catalog No.: HY-182719
• CAS No.: 2374807-41-5
• Molecular Formula: C14H28BN3O5
• Molecular Weight: 329.20
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source