PSB-16671

Overview

PSB-16671 is an allosteric agonist of GPR84 . PSB-16671 recruits β-arrestins and couples to Gi , enhances the Gi activation potency of orthosteric agonists, and exerts a synergistic effect with orthosteric agonists. PSB-16671 promotes G protein activation and partial chemotaxis independent of GPR84 in mouse neutrophils, maintains the phagocytic function of macrophages against cancer cells without inducing receptor desensitization. PSB-16671 can be used in cancer-related research.

Application

Products | Products > Disease Areas > Cancer | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > GPR84

Product Information

• Catalog No.: HY-182723
• CAS No.: 2094630-35-8
• Molecular Formula: C17H10F4N2
• Molecular Weight: 318.27
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source