SOAT-IN-2 is a selective sodium-dependent organic anion transporter ( SOAT , SLC10A6 ) inhibitor. SOAT-IN-2 blocks sodium-dependent cellular uptake of sulfated steroid Dehydroepiandrosterone sulfate (DHEAS, HY-113416). SOAT-IN-2 reduces intracellular estradiol synthesis, DHEA ( HY-14650 ) formation, and DHEA S-stimulated cancer cell proliferation without inducing cytotoxicity. SOAT-IN-2 can be used for the research of breast cancer .
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