JNJ-10450232

Overview

NTM-006 is a selective and brain-penetrant adenosine A3 receptor ( A3AR ) agonist. NTM-006 selectively interacts with adenosine A3AR via π-π stacking with Phe168 and π-alkyl interactions receptor residues. NTM-006 inhibits Acetic acid (HY-Y0319)-induced writhing responses in mice. NTM-006 can be used for the research of chronic neuropathic pain, cancer-related pain, osteoarthritis-associated pain.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Pain | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > Adenosine Receptor

Product Information

• Catalog No.: HY-182783
• CAS No.: 862248-40-6
• Molecular Formula: C11H11N3O2
• Molecular Weight: 217.22
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source