Multitarget AD-IN-7

Overview

Multitarget AD-IN-7 is an orally active multi-target anti-AD compound. Multitarget AD-IN-7 exhibits inhibitory activity against GSK-3β and GSK-3α ( IC 50 = 0.66, 0.83 nM). Multitarget AD-IN-7 upregulates the expression of p-GSK-3β-Ser9 , inhibits the phosphorylation of tau-Ser396 , targets Aβ 1-42 , chelates pathogenic metal ions, scavenges ABTS•+ , upregulates the expression of β-catenin and neurogenesis biomarkers, and promotes neurite outgrowth. Multitarget AD-IN-7 improves motor ability in Alzheimer's disease zebrafish. Multitarget AD-IN-7 is applicable to research related to Alzheimer's disease.

Application

Products | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Alzheimer's Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > GSK-3 | Products > Signaling Pathways > Tau Protein | Products > Signaling Pathways > Amyloid-β | Products > Signaling Pathways > β-catenin

Product Information

• Catalog No.: HY-182788
• CAS No.: 3113741-59-3
• Molecular Formula: C28H19N5O2
• Molecular Weight: 457.48
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source