LRRK2-IN-21 is a selective, blood-brain barrier-permeable LRRK2 kinase inhibitor with an IC 50 of 0.35 nM. LRRK2-IN-21 inhibits TTK kinase with an IC 50 of 70 nM. LRRK2-IN-21 is applicable to the research of Parkinson's disease.
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