NCD38

Overview

NCD38 is a Lysine-specific demethylase 1 ( LSD1 ) inhibitor with a target IC 50 of 0.59 μM. NCD38 selectively disrupts LSD1 - GFI1B interactions, dissociates LSD1 and CoREST from the ERG super-enhancer. NCD38 increases apoptosis -related protein levels, induces apoptosis and reduces SOX2 and Oct4 levels. NCD38 can be used for the research of acute myeloid leukemia.

Application

Products | Products > Disease Areas > Acute Myeloid Leukemia | Products > Disease Areas > Cancer | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Disease Areas > Leukemia/Lymphoma/Myeloma | Products > Disease Areas > Blood Disease | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Histone Demethylase | Products > Signaling Pathways > Apoptosis

Product Information

• Catalog No.: HY-183202
• CAS No.: 1456907-39-3
• Molecular Formula: C35H36ClN3O2
• Molecular Weight: 566.13
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source