BMS-869780

Overview

BMS-869780 is an orally active non-acidic γ-secretase ( γ-secretase ) modulator. BMS-869780 regulates the activity of γ-secretase , thereby altering the production profile of β-amyloid proteins. When acting alone, it changes the relative levels of specific β-amyloid subtypes without inhibiting the total production of β-amyloid proteins. BMS-869780 exerts a synergistic effect with γ-secretase modulators of the acidic structural class to inhibit the total production of β-amyloid proteins in cell cultures.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > Stem Cell/Wnt | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > γ-secretase | Products > Signaling Pathways > Amyloid-β

Product Information

• Catalog No.: HY-18326
• CAS No.: 1235493-78-3
• Molecular Formula: C23H22ClFN6O
• Molecular Weight: 452.92
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source