PI3Kα-IN-32

Overview

PI3Kα-IN-32 (Compound 11f) is a selective, orally active PI3Kα inhibitor, with an IC 50 of 26.3 nM against PI3Kα H1047R . PI3Kα-IN-32 inhibits AKT phosphorylation. PI3Kα-IN-32 exhibits anticancer activity against breast cancer . PI3Kα-IN-32 can be used in the research of HR + /HER2 - breast cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Breast Cancer | Products > Disease Areas > Luminal Breast Cancer | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Signaling Pathways > PI3K | Products > Signaling Pathways > Akt

Product Information

• Catalog No.: HY-183285
• CAS No.: 3057582-20-1
• Molecular Formula: C20H18F5N5O2S
• Molecular Weight: 487.45
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source