WEE1/PKMYT1-IN-4

Overview

WEE1/PKMYT1-IN-4 is a selective WEE1 / PKMYT1 inhibitor, with IC 50 values of 0.185 μM and 2.2 nM for human WEE1 and PKMYT1, respectively. WEE1/PKMYT1-IN-4 inhibits phosphorylation of CDK1 at T14 and Y15, disrupting the G2/M cell cycle checkpoint. WEE1/PKMYT1-IN-4 can be used for the research of colorectal cancer and amplified breast cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Breast Cancer | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Wee1 | Products > Signaling Pathways > CDK

Product Information

• Catalog No.: HY-183547
• CAS No.: 3055032-68-0
• Molecular Formula: C19H16FN5O2
• Molecular Weight: 365.36
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source