C5F2-HCB

Overview

C5F2-HCB is a CYP -mediated inhibitor of the biosynthesis of arachidonic acid epoxygenase product (±) 14,15-EET ( HY-150084 ), with an IC 50 of 3.1 μM. C5F2-HCB inhibits EET-driven oxidative phosphorylation ( OXPHOS ) associated with tumor hypoxia, converting an immunologically "cold" tumor microenvironment into a "hot" one. C5F2-HCB reverses the immune-excluded tumor microenvironment in ER + HER2 − breast cancer allograft models. C5F2-HCB can be used in research related to ER + HER2 − breast cancer .

Application

Products | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy

Product Information

• Catalog No.: HY-183844
• CAS No.: 2792206-44-9
• Molecular Formula: C17H25F2N5
• Molecular Weight: 337.41
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source