SPU-106

Overview

SPU-106 is a p21 activated kinase 4 ( PAK4 ) inhibitor with a target IC 50 of 21.36 μM. SPU-106 selectively binds to the C-terminal kinase domain of PAK4 to inhibit its kinase activity. SPU-106 inhibits the PAK4 / LIMK1 /cofilin and PAK4 / SCG10 signaling pathways. SPU-106 inhibits invasion of gastric cancer cells and lacks cytotoxicity against cancer cells. SPU-106 can be used for the research of gastric cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Gastric Cancer | Products > Disease Areas > Digestive System Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Research Areas > Cancer | Products > Signaling Pathways > PAK

Product Information

• Catalog No.: HY-183941
• CAS No.: 713080-84-3
• Molecular Formula: C22H17N3O3S
• Molecular Weight: 403.45
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source