LRRK2-IN-22

Overview

LRRK2-IN-22 is a LRRK2 inhibitor, with IC 50 values of 315.7 nM and 255.4 nM against LRRK2 WT and LRRK2 G2019S , respectively. LRRK2-IN-22 effectively inhibits LRRK2 kinase activity and downstream Rab10 phosphorylation, reduces ROS , and exhibits low cytotoxicity. LRRK2-IN-22 can be used for research on Parkinson's disease.

Application

Products | Products > Disease Areas > Parkinson's Disease | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Signaling Pathways > Autophagy | Products > Signaling Pathways > NF-κB | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > LRRK2 | Products > Signaling Pathways > Reactive Oxygen Species (ROS)

Product Information

• Catalog No.: HY-184198
• CAS No.: 1427947-55-4
• Molecular Formula: C21H21N3O2
• Molecular Weight: 347.41
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source