HDAC6-IN-84

Overview

HDAC6-IN-84 is a potent and selective HDAC6 inhibitor with an IC 50 of 25.56 nM and shows 478-fold selectivity over HDAC1 . HDAC6-IN-84 increases α-tubulin acetylation and upregulates BDNF (exons I and IV) and other neurogenesis-related genes. HDAC6-IN-84 can be used for the study of Alzheimer’s disease (AD) and other neurodegenerative diseases.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Alzheimer's Disease | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > HDAC

Product Information

• Catalog No.: HY-184424
• CAS No.: 3053402-10-8
• Molecular Formula: C17H16N2O3S
• Molecular Weight: 328.39
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source