RN193

RN193
  • CAS No.:3091508-49-2
  • Formula:C30H32N6O3
  • M.W.:524.61

Important Notice

  1. This product is a chemical product/pharmaceutical intermediate. It is not a drug, an active pharmaceutical ingredient (API), or a pharmaceutical-grade material. It has not been granted a drug approval number or a Chemical Drug Substance Approval Notice, has not passed drug-related review and approval, and is not manufactured, tested, or released in accordance with pharmaceutical GMP.
  2. This product is intended solely for non-clinical research, process development, quality studies, further chemical processing, or chemical synthesis. It must not be used in drug-product manufacturing, clinical trials, clinical diagnosis, or administration to humans or animals, or be sold, used as an input, submitted for regulatory filing, or released as an API or pharmaceutical material.
  3. The purchaser must not use this product, or supply it to another party, for personal consumption, sports or fitness, weight loss, health supplements, food, or animal feed.

Overview

RN193 is a type II kinase inhibitor with a human PAK1 IC 50 of 4.28 μM. RN193 functionally inhibits kinase activity of PAK1 , PAK2 , and PAK3 , and engages with their kinase domains in live cells. RN193 induces thermal shifts in CLK1 , GSK3B , ULK1 , MELK , MAPK13 , BRAF , and STK10 , indicating binding and stabilization of these proteins. RN193 induces formation of PAK3 : PAK2 heterodimers and displaces PAK2 homodimers in live cells. RN193 acts as a tool compound for studying group I PAK conformational states.

Application

Products | Products > Disease Areas > Others | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Cytoskeleton | Products > Research Areas > Others | Products > Signaling Pathways > PAK

Product Information

  • Catalog No.: HY-184447
  • CAS No.: 3091508-49-2
  • Molecular Formula: C30H32N6O3
  • Molecular Weight: 524.61
  • Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source


Welcome!

Please leave a message for us or use the following ways to contact us, we will reply to you as soon as possible, and provide you with the most sincere service, thank you.

  • NO. 18 ,Wujiang Road, Wulidian Street, Jiangbei District, Chongqing
  • +86-23-6139-8061 +86-13650506873
  • danny@chemdad.com sales@chemdad.com
  • www.chemdad.com
  • WhatsApp +86-13650506873

Name

phone

company

email

message

Read the full Disclaimer
Payment methods
Google translate: 日本语日本语 한국어한국어 FrançaisFrançais DeutschDeutsch EspañaEspaña TürkiyeTürkiye