SLL-022CCP

Overview

SLL-022CCP is a KOR -selective, high affinity and extremely potent agonist with an EC 50 of 9.1 nM and a K i of 2.0 nM. SLL-022CCP inhibits cAMP production with an EC 50 of 0.002 nM, and exhibits high receptor subtype selectivity over the μ-opioid receptor (MOR, EC 50 = 1.6 nM) and δ-opioid receptor (DOR, EC 50 = 30.0 nM). SLL-022CCP exhibits robust antinociceptive and antipruritic effects with low central side effects.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Pain | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Opioid Receptor

Product Information

• Catalog No.: HY-184476
• CAS No.: 2084834-44-4
• Molecular Formula: C31H34N2O4
• Molecular Weight: 498.61
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source