BPR1M492

Overview

BPR1M492 is a brain-penetrant μ-opioid receptor ( MOR ) agonist an in vitro EC 50 of 0.93 nM in the cAMP inhibition assay and 0.004 nM in the FLIPR Ca 2+ assay without a clear signaling bias between cAMP and β-arrestin-2 pathway. BPR1M492 is a cAMP-biased nociceptin-orphanin FQ opioid peptide agonist. BPR1M492 is a weak cAMP-biased δ/κ-opioid receptor agonist. BPR1M492 demonstrates potent in vivo antinociception and can be used for pain research.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Pain | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Opioid Receptor

Product Information

• Catalog No.: HY-184490
• CAS No.: 3118558-91-8
• Molecular Formula: C21H24N2O
• Molecular Weight: 320.43
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source