PDIC-DPC

Overview

PDIC-DPC is a HMGA1 inhibitor and lung-targeting agent. PDIC-DPC upregulates STING expression and enhances STING -mediated immune signaling. PDIC-DPC inhibits the TGFβ-Smad pathway and activates AMPK . PDIC-DPC forms nanocomplexes with fibrinogen β chain and vitronectin , and achieves lung-specific accumulation by binding to pulmonary endothelial receptors. PDIC-DPC reverses established pulmonary fibrosis, reduces collagen deposition, restores alveolar structure, improves pulmonary function, and inhibits in situ ESCC growth. PDIC-DPC can be used for the research of esophageal squamous cell carcinoma and idiopathic pulmonary fibrosis.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Melanoma | Products > Disease Areas > Pulmonary Disease | Products > Disease Areas > Squamous Cell Carcinoma | Products > Disease Areas > Lung Fibrosis | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > Stem Cell/Wnt | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Epigenetics | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Stem Cells | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > TGF-beta/Smad | Products > Signaling Pathways > AMPK | Products > Signaling Pathways > HMG Family | Products > Signaling Pathways > STING

Product Information

• Catalog No.: HY-184535
• CAS No.: 3008320-14-4
• Molecular Formula: C34H30Cl6N4O4
• Molecular Weight: 771.34
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source