DZ-1-DHA

Overview

DZ-1-DHA is a conjugate of DHA ( HY-B2167 ) and DZ-1 dye. DZ-1-DHA mediates selective cellular uptake via binding to overexpressed OATP1A2 . DZ-1-DHA induces the cleavage of Caspase-3 , Caspase-8 , Caspase-9 and PARP-1 . DZ-1-DHA induces Apoptosis and Ferroptosis . DZ-1-DHA induces ROS production through a Fenton-like mechanism, causes mitochondrial membrane depolarization, and triggers lipid peroxidation. DZ-1-DHA can be used in studies related to colorectal cancer liver metastasis.

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Digestive System Disease | Products > Disease Areas > Colorectal Cancer | Products > Disease Areas > Digestive System Cancer | Products > Signaling Pathways > Others | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > NF-κB | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > Drug Derivative | Products > Signaling Pathways > OAT | Products > Signaling Pathways > Caspase | Products > Signaling Pathways > PARP | Products > Signaling Pathways > Apoptosis | Products > Signaling Pathways > Ferroptosis | Products > Signaling Pathways > Reactive Oxygen Species (ROS)

Product Information

• Catalog No.: HY-184557
• CAS No.: 2223036-84-6
• Molecular Formula: C55H71ClN2O9S
• Molecular Weight: 971.68
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source