β2AR agonist 6

Overview

β2AR agonist 6 is a MABA with both muscarinic acetylcholine M 3 receptor antagonistic activity and β 2 adrenergic receptor agonistic activity, with a K i of 1.95 nM against hM 3 and an EC 50 of 0.266 nM against hβ 2 . β2AR agonist 6 binds to the M 3 muscarinic receptor with high affinity and exhibits long-lasting binding, while displaying subnanomolar agonist activity at the β2 adrenergic receptor . β2AR agonist 6 induces smooth muscle relaxation and provides long-lasting bronchoprotective effects. β2AR agonist 6 can be used in research related to asthma and chronic obstructive pulmonary disease .

Application

Products | Products > Disease Areas > Respiratory Inflammation | Products > Disease Areas > Lower Respiratory Inflammation | Products > Disease Areas > Chronic Obstructive Pulmonary Disease | Products > Disease Areas > Asthma | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Respiratory Disease | Products > Disease Areas > Pulmonary Disease | Products > Disease Areas > Chronic Disease and Inflammation | Products > Signaling Pathways > GPCR/G Protein | Products > Signaling Pathways > Neuronal Signaling | Products > Research Areas > Inflammation/Immunology | Products > Signaling Pathways > mAChR | Products > Signaling Pathways > Adrenergic Receptor

Product Information

• Catalog No.: HY-184680
• CAS No.: 3109318-04-6
• Molecular Formula: C45H53N5O7S
• Molecular Weight: 808.00
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source