MKI-2

Overview

MKI-2 is a selective MASTL inhibitor with an IC 50 of 37.44 nM. MKI-2 induces mitotic catastrophe resulting from the modulation of the MASTL-PP2A axis in breast cancer cells. MKI-2 reduces phospho-ENSA, total, phospho- c-Myc levels. MKI-2 inhibts cancer cells proliferation, migration and induces DNA damage. MKI-2 inhibits germinal vesicle breakdown in mouse oocytes. MKI-2 can be used for the research of cancer , such as breast cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Breast Cancer | Products > Signaling Pathways > Cell Cycle/DNA Damage | Products > Signaling Pathways > Cytoskeleton | Products > Signaling Pathways > Apoptosis | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Metabolism and Metastasis | Products > Signaling Pathways > MASTL | Products > Signaling Pathways > c-Myc | Products > Signaling Pathways > DNA/RNA Synthesis

Product Information

• Catalog No.: HY-185310
• CAS No.: 438204-56-9
• Molecular Formula: C22H19N7
• Molecular Weight: 381.43
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source