W-GTF01

Overview

W-GTF01 is a MGAT1 inhibitor. W-GTF01 blocks the MGAT1-catalyzed glycosylation of CD73 , and inhibits CD73 dimerization, membrane translocation and adenosine production. W-GTF01 restores the function of IFNγ-producing CD8 + T cells, enhances tumor infiltration and activation of CD8 + T cells, and suppresses tumor growth. W-GTF01 can be used in research related to triple-negative breast cancer .

Application

Products | Products > Disease Areas > Cancer | Products > Disease Areas > Breast Cancer | Products > Disease Areas > Triple-Negative Breast Cancer | Products > Signaling Pathways > Immunology/Inflammation | Products > Research Areas > Cancer | Products > Research Areas > Cancer > Cancer Targeted Therapy | Products > Research Areas > Cancer > Cancer Immunotherapy | Products > Signaling Pathways > CD73

Product Information

• Catalog No.: HY-185701
• CAS No.: 951968-89-1
• Molecular Formula: C24H20N2O5
• Molecular Weight: 416.43
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source