HCN-IN-1

Overview

HCN-IN-1 is a TLR4 inhibitor and HCN channel modulator with activity against HCN2 and HCN4 .HCN-IN-1 inhibits TLR4 -mediated alkaline phosphatase (SEAP) signal activity.HCN-IN-1 reduces HCN2 current across tested voltages, shifts voltage-dependent activation to more hyperpolarized potentials, slows activation kinetics, and does not affect deactivation process.HCN-IN-1 blocks HCN4 current.HCN-IN-1 exhibits analgesic, anti-inflammatory, and anti-anginal effects.HCN-IN-1 can be used for the research of inflammatory pain, neuropathic pain, heart failure, inflammation.

Application

Products | Products > Disease Areas > Inflammation or Immune System Disease | Products > Disease Areas > Cardiovascular Disease | Products > Disease Areas > Heart Disease | Products > Disease Areas > Pain | Products > Disease Areas > Heart Failure | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Blood or Cardio-cerebrovascular Disease | Products > Signaling Pathways > Immunology/Inflammation | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Research Areas > Neurological Disease | Products > Research Areas > Inflammation/Immunology | Products > Research Areas > Cardiovascular Disease | Products > Signaling Pathways > Toll-like Receptor (TLR) | Products > Signaling Pathways > Potassium Channel | Products > Signaling Pathways > Phosphatase

Product Information

• Catalog No.: HY-186062
• CAS No.: 2234283-04-4
• Molecular Formula: C28H38ClN3O2
• Molecular Weight: 484.07
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source