KARI 101

Overview

KARI 101 is a blood-brain barrier permeable acid sphingomyelinase ( ASM ) inhibitor. KARI 101 directly inhibits ASM activity and reduces ceramide production. KARI 101 induces Ca 2+ mobilization, activates AMPK and triggers GHSR1α internalization. KARI 101 can be used for the research of Alzheimer's disease.

Application

Products | Products > Disease Areas > Neurological, Eye or Ear Disease | Products > Disease Areas > Neurodegenerative Disease | Products > Disease Areas > Alzheimer's Disease | Products > Signaling Pathways > Metabolic Enzyme/Protease | Products > Signaling Pathways > PI3K/Akt/mTOR | Products > Signaling Pathways > Epigenetics | Products > Signaling Pathways > Membrane Transporter/Ion Channel | Products > Signaling Pathways > Neuronal Signaling | Products > Signaling Pathways > GPCR/G Protein | Products > Research Areas > Neurological Disease | Products > Signaling Pathways > Calcium Channel | Products > Signaling Pathways > GHSR | Products > Signaling Pathways > Phosphatase | Products > Signaling Pathways > AMPK

Product Information

• Catalog No.: HY-186165
• CAS No.: 3061559-97-2
• Molecular Formula: C15H30N4O2
• Molecular Weight: 298.42
• Storage: Please store the product under the recommended conditions in the Certificate of Analysis.

Source

Original product source